Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL
Ashish Sethi, Christopher R. Horne, Cheree Fitzgibbon, Karyn L. Wilde, Katherine A. Davies, Sarah E. Garnish, Annette V. Jacobsen, André L. Samson, Joanne M. Hildebrand, Ahmad Z. Wardak, Peter E. Czabotar, Emma J. Petrie, Paul R. Gooley, James M. Murphy
Topics & Concepts
NecroptosisEffectorBiologyCell biologyEpitopeLytic cycleProgrammed cell deathHelix (gastropod)PhosphorylationBiochemistryVirologyVirusGeneticsAntibodySnailApoptosisEcologyCell death mechanisms and regulationinterferon and immune responsesPARP inhibition in cancer therapy