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Non-arteritic Anterior Ischemic Optic Neuropathy with Macular Star following COVID-19 Vaccination

Abdelrahman M. Elhusseiny, Riley N. Sanders, Mohammad Z. Siddiqui, Ahmed B. Sallam

2022Ocular Immunology and Inflammation15 citationsDOI

Abstract

PURPOSE: To report a case of non-arteritic anterior ischemic optic neuropathy (NAAION) with macular star after receiving the second dose of SARS-CoV-2 vaccination. METHOD: Case report. OBSERVATION: A 51-year-old male presented with acute visual disturbances one day after the second dose of BNT162b2 mRNA SARS-CoV-2 vaccination. At presentation, best corrected visual acuity (BCVA) was 20/25 right eye (OD) and counting fingers at 3 feet left eye (OS). Anterior segment examination was normal in both eyes. Dilated fundoscopy was unremarkable OD, however, it disclosed optic nerve swelling and subretinal fluid OS. Patient was treated with a gradual tapering dose of oral prednisone over 1 month. At the five-week follow-up visit, optic disc swelling and subretinal fluid resolved with minimal improvement in BCVA to 20/400 OS. CONCLUSION: It is unclear whether COVID-19 vaccination was the triggering agent to the NAAION or just a coincidence, yet ophthalmologists should be aware of such a possible association.

Topics & Concepts

MedicineOphthalmologyCoronavirus disease 2019 (COVID-19)Anterior ischemic optic neuropathyOptic neuropathy2019-20 coronavirus outbreakOptic nerveInternal medicineDiseaseVirologyOutbreakInfectious disease (medical specialty)Retinal and Optic ConditionsIntraoperative Neuromonitoring and Anesthetic EffectsSARS-CoV-2 and COVID-19 Research
Non-arteritic Anterior Ischemic Optic Neuropathy with Macular Star following COVID-19 Vaccination | Litcius