Litcius/Paper detail

Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine

Yanhong Duo, Lei Han, Yaoqiang Yang, Zhifeng Wang, Lirong Wang, Jingyi Chen, Zhongyuan Xiang, Juyoung Yoon, Guanghong Luo, Ben Zhong Tang

2024Chemical Reviews98 citationsDOIOpen Access PDF

Abstract

. This review seeks to present the latest advances in AIEgen-based biofluorescent probes for biopsy in real or artificial samples, and also the key properties of these AIE probes. This review is divided into: (i) tissue biopsy based on smart AIEgens, (ii) blood sample biopsy based on smart AIEgens, (iii) urine sample biopsy based on smart AIEgens, (iv) saliva sample biopsy based on smart AIEgens, (v) biopsy of other liquid samples based on smart AIEgens, and (vi) perspectives and conclusion. This review could provide additional guidance to motivate interest and bolster more innovative ideas for further exploring the applications of various smart AIEgens in precision medicine.

Topics & Concepts

ChemistryAggregation-induced emissionQuenching (fluorescence)FluorescenceBiopsyQuantum yieldNanotechnologyBiophysicsPathologyOpticsMaterials scienceMedicineBiologyPhysicsLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranosticsSupramolecular Self-Assembly in Materials