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Static magnetic field on behavior, hematological parameters and organ damage in spontaneously hypertensive rats

Tatjana Tasić, Maja Lozić, Sofija Glumac, Marija Stanković, Ivan D. Milovanovich, Drago M. Djordjevich, Alexander M. Trbovich, Nina Japundžić‐Žigon, Silvio R. De Luka

2020Ecotoxicology and Environmental Safety20 citationsDOIOpen Access PDF

Abstract

Previous studies showed contradictory results of static magnetic field (SMF) influence on behavior, hematological parameters and organ damage. The aim of this study was to investigate influence of subchronic continuous exposure to upward and downward oriented SMF of moderate intensity on behavior, hematological characteristics, heart and kidney tissue of spontaneously hypertensive rats. SH rats exposed to downward oriented SMF demonstrated lack of anxious-like behavior. SMF of either orientation caused decrease in the number of platelets in peripheral blood, granulocytes in the spleen and bone marrow and increase in the number of erythrocytes in the spleen, in both exposed groups. We also demonstrated that spontaneously hypertensive rats exposed to upward oriented SMF exhibited decreased lymphocytes count in blood, decreased bone marrow erythrocytes count and rats exposed to downward oriented SMF had increased lymphocytes count in bone marrow. The results showed adverse effect of differently oriented SMF on hematological parameters of spontaneously hypertensive rats. Also, exposure to different oriented SMF didn't affect their heart and kidney morphological characteristics.

Topics & Concepts

SpleenBone marrowKidneyPlateletPeripheral bloodInternal medicineMedicineEndocrinologyHematologyPeripheralPathologyElectromagnetic Fields and Biological EffectsSpaceflight effects on biologyCircadian rhythm and melatonin