Handheld Point-of-Care System for Rapid Detection of SARS-CoV-2 Extracted RNA in under 20 min
Jesús Rodríguez-Manzano, Kenny Malpartida-Cardenas, Nicolas Moser, Ivana Pennisi, Matthew L. Cavuto, Luca Miglietta, Ahmad Moniri, Rebecca Penn, Giovanni Satta, Paul Randell, Frances Davies, Frances Bolt, William Barclay, Alison Holmes, Pantelis Georgiou
Abstract
= 34), demonstrating a comparable performance to a benchtop commercial instrument. Paired with a smartphone for results visualization and geolocalization, this portable diagnostic platform with secure cloud connectivity will enable real-time case identification and epidemiological surveillance.
Topics & Concepts
Loop-mediated isothermal amplificationPoint-of-care testingSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Point of careCoronavirus disease 2019 (COVID-19)Detection limitRNAMedicineVirologyChromatographyBiologyPathologyChemistryDiseaseInfectious disease (medical specialty)GeneticsGeneDNABiochemistryBiosensors and Analytical DetectionSARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniques