Klotho ameliorates diabetic nephropathy via LKB1-AMPK-PGC1α-mediated renal mitochondrial protection
Jinho Lee, Bodokhsuren Tsogbadrakh, Seunghee Yang, Hyunjin Ryu, Eunjung Kang, Minjung Kang, Hee Gyung Kang, Curie Ahn, Kook‐Hwan Oh
Topics & Concepts
Mitochondrial biogenesisAMPKEndocrinologyInternal medicineTFAMKlothoMitochondrionKidneyAMP-activated protein kinaseMitochondrial ROSDiabetic nephropathyChemistryBiologyOxidative stressProtein kinase AMedicineCell biologyPhosphorylationParathyroid Disorders and TreatmentsGenetic Syndromes and ImprintingBiomedical Research and Pathophysiology