Biochemical and structural cues of 3D-printed matrix synergistically direct MSC differentiation for functional sweat gland regeneration
Bin Yao, Rui Wang, Yihui Wang, Yijie Zhang, Tian Hu, Wei Song, Zhao Li, Sha Huang, Xiaobing Fu
Abstract
synergistically boosted SG gene expression profile. Together, these findings indicated that biochemical and structural cues served as two critical impacts of 3D-printed matrix on MSC fate decision into the glandular lineage and functional SG recovery.
Topics & Concepts
Regeneration (biology)Sweat gland3d printedMatrix (chemical analysis)Cell biologySWEATBiologyExtracellular matrixAnatomyComputer scienceMaterials scienceBiomedical engineeringMedicineComposite materialPaleontology3D Printing in Biomedical ResearchAdditive Manufacturing and 3D Printing TechnologiesPlanarian Biology and Electrostimulation