Machine learning-empowered <i>cis</i>-diol metabolic fingerprinting enables precise diagnosis of primary liver cancer
Pengfei Li, Shuxin Xu, Yanjie Han, Hui He, Zhen Liu
Abstract
A mass spectrometric platform was built for in-depth profiling of mutational landscape of cis -diol metabolites from the healthy to primary liver cancer (PLC) patients. This method enabled more precise PLC diagnosis than protein marker-based methods.
Topics & Concepts
CancerPrimary (astronomy)Computer scienceArtificial intelligenceDiolComputational biologyMachine learningChemistryMedicineBiologyInternal medicinePhysicsOrganic chemistryAstronomyMetabolomics and Mass Spectrometry StudiesCancer, Hypoxia, and MetabolismNanoplatforms for cancer theranostics