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Nuclear accumulation of pyruvate dehydrogenase alpha 1 promotes histone acetylation and is essential for zygotic genome activation in porcine embryos

Wenjun Zhou, Yingjie Niu, Zheng‐Wen Nie, Juyeon Kim, Yong‐Nan Xu, Chang−Guo Yan, Xiang‐Shun Cui

2020Biochimica et Biophysica Acta (BBA) - Molecular Cell Research41 citationsDOI

Topics & Concepts

Maternal to zygotic transitionPyruvate dehydrogenase complexBiologyAcetylationHistoneEpigeneticsCell biologyEmbryoMolecular biologyZygoteEmbryogenesisGeneticsBiochemistryGeneEnzymePluripotent Stem Cells ResearchEpigenetics and DNA MethylationMitochondrial Function and Pathology
Nuclear accumulation of pyruvate dehydrogenase alpha 1 promotes histone acetylation and is essential for zygotic genome activation in porcine embryos | Litcius