Efficient Synthesis and Docking Studies of Novel Benzothiazole-Based Pyrimidinesulfonamide Scaffolds as New Antiviral Agents and Hsp90α Inhibitors
Rasha A. Azzam, Rokia R. Osman, Galal H. Elgemeie
Abstract
were also docked inside the active site of Hsp90α to assess the interaction pattern between the tested compounds and the active site of the protein.
Topics & Concepts
BenzothiazoleDocking (animal)Combinatorial chemistryChemistryHsp90Computational biologyPharmacologyBiochemistryBiologyMedicineHeat shock proteinNursingGeneAlcohol Consumption and Health EffectsHepatitis C virus researchGenomics, phytochemicals, and oxidative stress