Litcius/Paper detail

Microbiota-Dependent and -Independent Production of <scp>l-</scp> Dopa in the Gut of Daphnia magna

Rehab El-Shehawy, Sandra Luecke-Johansson, Anton Ribbenstedt, Elena Gorokhova

2021mSystems13 citationsDOIOpen Access PDF

Abstract

and its gut microbiome contribute to the synthesis of the l-Dopa in the gut. We also identified a peripheral pathway in the gut wall, with a molt stage-dependent dopamine synthesis, linking the gut microbiome to the daphnid development and growth. These findings suggest a central role of l-Dopa in the bidirectional communication between the animal host and its gut bacteria and translating into the ecologically important host traits suitable for subsequent testing of causality by experimental studies.

Topics & Concepts

BiologyGut floraDaphniaMicrobiomeTyrosine hydroxylaseAromatic L-amino acid decarboxylaseDopamineVertebrateGut bacteriaGut microbiomeHost (biology)NeurotransmitterBacteriaDaphnia magnaModel organismEnzymeCell biologyGeneBiochemistryEvolution and Genetic DynamicsBacterial Genetics and BiotechnologyEvolutionary Game Theory and Cooperation