Microbiota-Dependent and -Independent Production of <scp>l-</scp> Dopa in the Gut of Daphnia magna
Rehab El-Shehawy, Sandra Luecke-Johansson, Anton Ribbenstedt, Elena Gorokhova
Abstract
and its gut microbiome contribute to the synthesis of the l-Dopa in the gut. We also identified a peripheral pathway in the gut wall, with a molt stage-dependent dopamine synthesis, linking the gut microbiome to the daphnid development and growth. These findings suggest a central role of l-Dopa in the bidirectional communication between the animal host and its gut bacteria and translating into the ecologically important host traits suitable for subsequent testing of causality by experimental studies.
Topics & Concepts
BiologyGut floraDaphniaMicrobiomeTyrosine hydroxylaseAromatic L-amino acid decarboxylaseDopamineVertebrateGut bacteriaGut microbiomeHost (biology)NeurotransmitterBacteriaDaphnia magnaModel organismEnzymeCell biologyGeneBiochemistryEvolution and Genetic DynamicsBacterial Genetics and BiotechnologyEvolutionary Game Theory and Cooperation