Benzofuran pyran compound rescues rat and human osteoblast from lipotoxic effect of palmitate by inhibiting lipid biosynthesis and promoting stabilization of RUNX2
Ashish Kumar Tripathi, Divya Rai, Priyanka Kothari, Pragati Kushwaha, Shradha Sinha, Anirban Sardar, Koneni V. Sashidhara, Ritu Trivedi
Topics & Concepts
RUNX2LipotoxicityChemistryEndocrinologyInternal medicineOsteoblastLipid dropletFatty acid synthesisAdipocyteFatty acidApoptosisBiochemistryBiologyAdipose tissueIn vitroMedicineInsulin resistanceInsulinCancer, Lipids, and MetabolismDrug-Induced Hepatotoxicity and ProtectionPeroxisome Proliferator-Activated Receptors