Luteolin ameliorates chronic stress-induced depressive-like behaviors in mice by promoting the Arginase-1+ microglial phenotype via a PPARγ-dependent mechanism
Naijun Yuan, Wenjun Zhu, Qingyu Ma, Min-yi Huang, Rou-rou Huo, Kai-jie She, Jun-ping Pan, Jigang Wang, Jiaxu Chen
Topics & Concepts
ArginasePhenotypeMechanism (biology)Peroxisome proliferator-activated receptorChronic stressOxidative stressLuteolinPharmacologyMedicineImmunologyChemistryInternal medicineReceptorGeneBiochemistryArginineFlavonoidPhilosophyAntioxidantAmino acidEpistemologyTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol