DNA damage by reactive oxygen species resulting from metabolic activation of 8-epidiosbulbin E acetate in vitro and in vivo
Shiyu Zhang, Ying Liu, Ting Liu, Jie Pan, Rong Tan, Zixia Hu, Bowen Gong, Yufen Liao, Peng Luo, Qibing Zeng, Weiwei Li, Jiang Zheng
Topics & Concepts
DNA damageReactive oxygen speciesDNA fragmentationGlutathioneChemistryIn vivoButhionine sulfoximineMolecular biologyBiochemistryCytotoxicityDNAIn vitroBiologyApoptosisProgrammed cell deathEnzymeBiotechnologyPotato Plant ResearchCarcinogens and Genotoxicity AssessmentDrug-Induced Hepatotoxicity and Protection