Protective effect of quercetin against 5-fluorouracil-induced cardiac impairments through activating Nrf2 and inhibiting NF-κB and caspase-3 activities
Maha S. Lokman, Hussam A. Althagafi, Fahad Alharthi, Ola A. Habotta, Arwa A. Hassan, Mohamed Elhefny, Hassan Al Sberi, Abdulrahman Theyab, Ahmad H. Mufti, Alaa Alhazmi, Yousef M. Hawsawi, Asmaa F. Khafaga, Mahmoud S. Gewaily, Khalaf F. Alsharif, Ashraf Albrakati, Rami B. Kassab
Topics & Concepts
Glutathione peroxidaseCardiotoxicityMalondialdehydePharmacologySuperoxide dismutaseLactate dehydrogenaseChemistryAntioxidantGlutathioneTumor necrosis factor alphaEndocrinologyInternal medicineMedicineToxicityBiochemistryEnzymeChemotherapy-induced cardiotoxicity and mitigationChemotherapy-induced organ toxicity mitigationGenomics, phytochemicals, and oxidative stress