Circ_0082374 Promotes the Tumorigenesis and Suppresses Ferroptosis in Non-small Cell Lung Cancer by Up-Regulating GPX4 Through Sequestering miR-491-5p
Zongyu Li, Mengdi Fan, Zhibo Zhou, Xianyin Sang
Topics & Concepts
GPX4Competing endogenous RNAGene knockdownCarcinogenesisCell growthCancer researchEpithelial–mesenchymal transitionChemistryGene silencingTumor progressionA549 cellCellBiologyDownregulation and upregulationMolecular biologyCancerMetastasisGlutathione peroxidaseBiochemistryOxidative stressCatalaseApoptosisLong non-coding RNAGeneGeneticsCircular RNAs in diseasesCancer-related molecular mechanisms researchMicroRNA in disease regulation