Catheter ablation for atrial fibrillation is associated with reduced risk of mortality in the elderly: a prospective cohort study and propensity score analysis.
Xin Su, Xin Du, Shangxin Lu, Chao Jiang, Jing Du, Shijun Xia, Zhaojie Dong, Zhaoxu Jia, Deyong Long, Caihua Sang, Ribo Tang, Nian Liu, Songnan Li, Rong Bai, Jianzeng Dong, Changsheng Ma
Abstract
BACKGROUND: It is unclear whether catheter ablation (CA) for atrial fibrillation (AF) affects the long-term prognosis in the elderly. This study aims to evaluate the relationship between CA and long-term outcomes in elderly patients with AF. METHODS: Patients more than 75 years old with non-valvular AF were prospectively enrolled between August 2011 and December 2017 in the Chinese Atrial Fibrillation Registry Study. Participants who underwent CA at baseline were propensity score matched (1:1) with those who did not receive CA. The outcome events included all-cause mortality, cardiovascular mortality, stroke/transient ischemic attack (TIA), and cardiovascular hospitalization. RESULTS: = 0.1084). Subgroup analyses according to gender, type of AF, time since onset of AF, and anticoagulants exposure in initiation did not show significant heterogeneity. CONCLUSIONS: In elderly patients with AF, CA may be associated with a lower incidence of all-cause and cardiovascular mortality.