Identification and anticoagulant mechanisms of novel factor XIa inhibitory peptides by virtual screening of a in silico generated deep-sea peptide database
Yuhong Ouyang, Yue Yang, Ning Wu, Jing Wang, Lihua Geng, Quanbin Zhang
Topics & Concepts
In silicoVirtual screeningIdentification (biology)PeptideComputational biologyInhibitory postsynaptic potentialDatabaseChemistryBiologyComputer scienceBiochemistryDrug discoveryGeneNeuroscienceEcologyComputational Drug Discovery MethodsProtein Hydrolysis and Bioactive PeptidesCoagulation, Bradykinin, Polyphosphates, and Angioedema