Fluorinated cryptophane-A and porphyrin-based theranostics for multimodal imaging-guided photodynamic therapy
Huaibin Zhang, Yu Qiao, Haijun Yu, Zhigang Yang, Xin Zhou, Shizhen Chen, Zhong‐Xing Jiang
Abstract
Herein, we developed fluorinated nanoemulsions with significantly enhanced <italic>in vitro</italic> and <italic>in vivo</italic><sup>129</sup>Xe hyper-CEST MRI, <sup>19</sup>F MRI and fluorescence imaging signals for selective and sensitive tumor detection and NIR-activated photodynamic therapy.
Topics & Concepts
Photodynamic therapyPorphyrinFluorescenceFluorescence-lifetime imaging microscopyMaterials scienceChemistryBiomedical engineeringNanotechnologyMedicinePhotochemistryOpticsOrganic chemistryPhysicsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesCancer, Hypoxia, and Metabolism