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Targeting MALAT1 induces DNA damage and sensitize non-small cell lung cancer cells to cisplatin by repressing BRCA1

Jinghua Huang, Changxiu Lin, Hai Dong, Zhengri Piao, Chun-hua Jin, Hengmin Han, Dongchun Jin

2020Cancer Chemotherapy and Pharmacology42 citationsDOI

Topics & Concepts

MALAT1Cancer researchDNA repairCisplatinDNA damageCompeting endogenous RNABiologyViability assayMolecular biologymicroRNAAdenocarcinomaApoptosisLong non-coding RNARNACancerDNAGeneGeneticsChemotherapyCancer-related molecular mechanisms researchMicroRNA in disease regulationCircular RNAs in diseases
Targeting MALAT1 induces DNA damage and sensitize non-small cell lung cancer cells to cisplatin by repressing BRCA1 | Litcius