Copper-catalyzed aerobic oxidation of primary alcohols to carboxylic acids
Yibo Yu, Di Zhai, Zhengnan Zhou, Sheng Jiang, Hui Qian, Shengming Ma
Abstract
as the co-catalysts has been developed. The reaction exhibits excellent substrate scope and functional group compatibility under mild conditions. Even the very sensitive chiral alcohols, chiral amino alcohols, and alcohol-containing steroid skeletons may be oxidized to afford the corresponding carboxylic acids or lactones without racemization.
Topics & Concepts
RacemizationPrimary (astronomy)ChemistryAlcohol oxidationCatalysisAlcoholCopperOrganic chemistryFunctional groupCarboxylic acidSubstrate (aquarium)Primary alcoholCombinatorial chemistryAstronomyOceanographyGeologyPhysicsPolymerOxidative Organic Chemistry ReactionsSynthesis and Catalytic ReactionsAlkaloids: synthesis and pharmacology