Bacteriophage λ exonuclease and a 5′-phosphorylated DNA guide allow PAM-independent targeting of double-stranded nucleic acids
Shengnan Fu, Junjie Li, Jing Chen, Linghao Zhang, Jiajia Liu, Huiyu Liu, Xin Su
Topics & Concepts
Nucleic acidExonucleaseBacteriophageDNAChemistryDouble strandedBiochemistryMolecular biologyBiologyDNA polymeraseEscherichia coliGeneAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringBacteriophages and microbial interactions