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Structural and dynamic insights into the HNH nuclease of divergent Cas9 species

Helen B Belato, Alexandra M. D’Ordine, Łukasz Nierzwicki, Pablo R. Arantes, G. Jogl, Giulia Palermo, George P. Lisi

2021Journal of Structural Biology22 citationsDOIOpen Access PDF

Topics & Concepts

Cas9NucleaseEndonucleaseCRISPRDNAComputational biologyBiologyRNAThermophileProtein structureProtein domainMolecular dynamicsMolecular machineGeneticsBiophysicsBiochemistryChemistryEnzymeGeneComputational chemistryCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsAdvanced biosensing and bioanalysis techniques
Structural and dynamic insights into the HNH nuclease of divergent Cas9 species | Litcius