Oxidative stress- and mitochondrial dysfunction-mediated cytotoxicity by silica nanoparticle in lung epithelial cells from metabolomic perspective
Xinying Zhao, Alimire Abulikemu, Songqing Lv, Yi Qi, Junchao Duan, Jie Zhang, Rui Chen, Caixia Guo, Yanbo Li, Zhiwei Sun
Topics & Concepts
Oxidative stressMetabolomicsGlutathioneDNA damageReactive oxygen speciesMitochondrionBiochemistryCytotoxicityChemistryOxidative phosphorylationToxicityCell biologyBiologyBioinformaticsIn vitroDNAOrganic chemistryEnzymeMetabolomics and Mass Spectrometry StudiesNanoplatforms for cancer theranosticsAdvanced Nanomaterials in Catalysis