Label-free imaging of human brain tissue at subcellular resolution for potential rapid intra-operative assessment of glioma surgery
Defu Chen, David W. Nauen, Hyeon‐Cheol Park, Dawei Li, Wu Yuan, Ang Li, Honghua Guan, Carmen Kut, Kaisorn L. Chaichana, Chetan Bettegowda, Alfredo Quiñones‐Hinojosa, Xingde Li
Abstract
Multiphoton imaging correlates well with histopathology and is a promising tool for characterization of cancer and delineation of infiltration within seconds during brain surgery.
Topics & Concepts
HistopathologyAutofluorescenceFrozen section procedurePathologyGliomaMedicineWhite matterBiomedical engineeringRadiologyMagnetic resonance imagingCancer researchOpticsPhysicsFluorescenceAdvanced Fluorescence Microscopy TechniquesPhotoacoustic and Ultrasonic ImagingCell Image Analysis Techniques