The effect of gradual ovarian failure on dynamic muscle function and the role of high-intensity interval training on mitigating impairments
Emma F. Hubbard, Parastoo Mashouri, W. Glen Pyle, Geoffrey A. Power
Abstract
We used the VCD model of menopause to investigate the effects of gradual ovarian failure on skeletal muscle contractile function and whether high-intensity interval training (HIIT) can mitigate impairments. Our findings indicate that ovarian failure impairs dynamic contractile function-likely through a combination of lower force-generating capacity and slower shortening velocity-and that HIIT may be insufficient to completely counteract the deleterious effects of menopause at the cellular level.
Topics & Concepts
High-intensity interval trainingInterval trainingIntensity (physics)Interval (graph theory)Physical medicine and rehabilitationTraining (meteorology)Function (biology)MedicinePhysical therapyMathematicsBiologyPhysicsQuantum mechanicsMeteorologyCombinatoricsEvolutionary biologyCardiovascular and exercise physiologyMuscle metabolism and nutritionExercise and Physiological Responses