<i>COCOMAPS</i> 2.0: a web server for identifying, analyzing, and visualizing atomic interactions at the interface of biomolecular complexes
Mohit Chawla, Utkarsh Kalra, Andrea Petta, Suraj Sharma, Abdul Rajjak Shaikh, Luigi Cavallo, Romina Oliva
Abstract
SUMMARY: Herein, we present COCOMAPS 2.0, for the analysis, visualization, and comparison of the interface in protein-protein and protein-nucleic acid complexes. COCOMAPS 2.0 complements the residue-level and buried surface area analyses of the original COCOMAPS tool with a comprehensive and accurate atomic-level characterization of the interface, enabling detailed interpretation of molecular recognition. Furthermore, it provides a greatly enhanced flexibility, interactivity, and efficiency in graphical visualizations. AVAILABILITY AND IMPLEMENTATION: COCOMAPS 2.0 is accessible as a public web tool at https://aocdweb.com/BioTools/cocomaps2 and as a standalone code at https://doi.org/10.5281/zenodo.17390665.