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Study on the mechanism of lignin and lignin-carbohydrate complex hydrolysis under alkaline conditions by density functional theory

J. Mao, Mingfu Zu, Ruilin Wu, Chao Xiao, Jian Kang, Fan Yahong

2024Biomass and Bioenergy27 citationsDOIOpen Access PDF

Abstract

Lignin hydrolyzes during alkali-heat pretreatment of lignocellulose , due to the cleavage of covalent linkages between lignin and lignin-carbohydrate complex. Various structure of lignin monomers are responsible of the complicated hydrolysis mechanism of lignin and lignin-carbohydrate complex. This study used density functional theory to reveal the hydrolysis mechanism of lignin with various substituents and lignin-carbohydrates complex with different linkages. The results indicated that the S N 2 reaction was observed to take place in the lignin. Methoxy groups and methyl group had an insignificant influence on hydrolysis reaction pathway of lignin, whereas the presence of a methyl group on the α-carbon atom had a hindering effect on the nucleophilic attack during alkaline pretreatment . The lignin-carbohydrate complex with different linkage showed a significant difference in hydrolysis reaction pathway. Additionally, the reaction energy barrier of ester bond hydrolysis was lowest among the hydrolysis of ester bond, phenyl glycosidic bond , benzyl ether bond, γ-ester bond, coumarin ester bond and acetal bond under alkaline condition. This study provides valuable insights into the process control, reactor design, and performance enhancement for lignocellulose pretreatment .

Topics & Concepts

LigninChemistryHydrolysisSN2 reactionOrganic chemistryAlkaline hydrolysisEtherBond cleavageNucleophileNucleophilic substitutionCarbohydrateCovalent bondCatalysisLignin and Wood ChemistryBiofuel production and bioconversionCatalysis for Biomass Conversion
Study on the mechanism of lignin and lignin-carbohydrate complex hydrolysis under alkaline conditions by density functional theory | Litcius