Palladium-catalyzed asymmetric [3 + 2] cycloaddition of vinyl aziridines and α,β-unsaturated imines generated <i>in situ</i> from aryl sulfonyl indoles
Shan Xiao, Bo Chen, Qin Jiang, Long He, Wen‐Dao Chu, Cheng‐Yu He, Quan‐Zhong Liu
Abstract
The first palladium-catalyzed asymmetric formal [3 + 2] cycloaddition of vinyl aziridines and <italic>in situ</italic> generated unsaturated imines has been established.
Topics & Concepts
CycloadditionChemistryPalladiumSulfonylCatalysisArylIn situOrganic chemistryMedicinal chemistryAlkylSynthesis and Catalytic ReactionsCatalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms