Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1)
Lihua Liu, Aihua Liu, Jun Dong, Zhongfu Zuo, Jun Dong, Zhongfu Zuo, Liu Xue-zheng
Topics & Concepts
BiologyPTENCancer researchSmall hairpin RNAProteasomeDownregulation and upregulationA549 cellCell cycleKinaseGene knockdownCell biologyPINK1ApoptosisSignal transductionMitophagyPI3K/AKT/mTOR pathwayBiochemistryAutophagyGeneUbiquitin and proteasome pathwaysPeptidase Inhibition and AnalysisRNA modifications and cancer