Amoxicillin or tetracycline in bismuth-containing quadruple therapy as first-line treatment for <i>Helicobacter pylori</i> infection
Chang Seok Bang, Hyun Lim, Hae Min Jeong, Woon Geon Shin, Jae Ho Choi, Jae Seung Soh, Ho Suk Kang, Young Joo Yang, Ji Taek Hong, Suk Pyo Shin, Ki Tae Suk, Jae Jun Lee, Gwang Ho Baik, Dong Joon Kim
Abstract
AIM: infection. METHODS: . RESULTS: > .99) analyses. Non-inferiority in the eradication success between PAMB and PBMT was confirmed. The amoxicillin-, metronidazole-, tetracycline-, clarithromycin-, and levofloxacin-resistance rates were 8.3, 40, 9.4, 23.5, and 42.2%, respectively. Antimicrobial resistance did not significantly affect the efficacy of either therapy. Overall compliance was 98.1%. Adverse events were not significantly different between the two therapies. CONCLUSION: infection in regions with high clarithromycin and metronidazole resistance.