Nose-to-brain delivery of simvastatin mediated by chitosan-coated lipid-core nanocapsules allows for the treatment of glioblastoma in vivo
Franciele Aline Bruinsmann, Aline de Cristo Soares Alves, Amanda de Fraga Dias, Luiz Fernando Lopes Silva, Fernanda Visioli, Adriana Raffin Pohlmann, Fabrício Figueiró, Fabio Sonvico, Sı́lvia Stanisçuaski Guterres
Topics & Concepts
NanocapsulesIn vivoPharmacologySimvastatinGliomaChemistryNasal administrationCytotoxicityChitosanIn vitroMedicineCancer researchBiologyNanotechnologyMaterials scienceBiochemistryNanoparticleBiotechnologyRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryAdvanced Drug Delivery Systems