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NLRC4 gene silencing-dependent blockade of NOD-like receptor pathway inhibits inflammation, reduces proliferation and increases apoptosis of dendritic cells in mice with septic shock

Shisheng Wang, Chun-Song Yan, Junming Luo

2021Aging15 citationsDOIOpen Access PDF

Abstract

silencing ameliorates lung injury and inflammation induced by septic shock by negatively regulating the NLR pathway.

Topics & Concepts

Gene silencingNLRC4InflammationApoptosisCancer researchCD80Cell biologyInflammasomeBiologyChemistryImmunologyCaspase 1Cytotoxic T cellCD40GeneIn vitroBiochemistryImmune Response and InflammationInflammasome and immune disordersSepsis Diagnosis and Treatment
NLRC4 gene silencing-dependent blockade of NOD-like receptor pathway inhibits inflammation, reduces proliferation and increases apoptosis of dendritic cells in mice with septic shock | Litcius