The prefrontal cortex hemodynamic responses to dual-task paradigms in older adults: A systematic review and meta-analysis
Kulvara Lapanan, Phunsuk Kantha, Gallayaporn Nantachai, Solaphat Hemrungrojn, Michaël Maes
Abstract
Background: Functional near-infrared spectroscopy (fNIRS) is a method to measure cerebral hemodynamics. Determining the changes in prefrontal cortex (PFC) hemodynamics during dual-task paradigms is essential in explaining alterations in physical activities, especially in older adults. Aims: To systematically review and meta-analyze the effects of dual-task paradigms on PFC hemodynamics in older adults. Methods: statistic. Additionally, subgroup analysis was conducted to compare the effects of different types of cognitive tasks. Results: < 0.01, 95% CI = -0.13 to -0.02), but did not change during working memory tasks. Conclusion: Cognitive tasks related to inhibitory control required greater cognitive demands, indicating higher pfc activation during dual-task paradigms in older adults. for clinical implications, the increase in pfc oxygenated hemoglobin and decrease in pfc deoxygenated hemoglobin may help explain why older adults are more likely to fall during daily activities.