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High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo

Sebastian G. Huayamares, Melissa P. Lokugamage, Regina Rab, Alejandro J. Da Silva Sanchez, Hyejin Kim, Afsane Radmand, David Loughrey, Liming Lian, Yuning Hou, Bhagelu R. Achyut, Annette Ehrhardt, Jeong S. Hong, Cory D. Sago, Kalina Paunovska, Elisa Schrader Echeverri, Daryll Vanover, Philip J. Santangelo, Eric J. Sorscher, James E. Dahlman

2023Journal of Controlled Release65 citationsDOIOpen Access PDF

Topics & Concepts

In vivoHead and neck squamous-cell carcinomaCancer researchNucleic acidChemistryMessenger RNACancerBiologyMedicineHead and neck cancerBiochemistryGeneInternal medicineBiotechnologyRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesSARS-CoV-2 and COVID-19 Research
High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo | Litcius