Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity
Jin Peng, Kun Jiang, Xiao Sun, Lingzhi Wu, Jiewei Wang, Xiaomei Xi, Xu Tan, Tingbo Liang, Chang‐Heng Tan, Pumin Zhang
Topics & Concepts
Broad spectrumIdentification (biology)Computational biologyClass (philosophy)CancerMedicineBiologyChemistryGeneticsComputer scienceCombinatorial chemistryArtificial intelligenceBotanyUbiquitin and proteasome pathwaysPARP inhibition in cancer therapyPeptidase Inhibition and Analysis