Bone health in pediatric patients with neurological disorders
Ara Ko, Juhyun Kong, Furkat Samadov, Akmal Mukhamedov, Young Mi Kim, Yun Jin Lee, Sang Ook Nam
Abstract
Patients with neurological disorders are at high risk of developing osteoporosis, as they possess multiple risk factors leading to low bone mineral density. Such factors include inactivity, decreased exposure to sunlight, poor nutrition, and the use of medication or treatment that can cause lower bone mineral density such as antiepileptic drugs, ketogenic diet, and glucocorticoids. In this article, mechanisms involved in altered bone health in children with neurological disorders and management for patients with epilepsy, cerebral palsy, and Duchenne muscular dystrophy regarding bone health are reviewed.
Topics & Concepts
MedicineBone healthPediatricsPhysical therapyOsteoporosisPathologyBone mineralPharmacological Effects and Toxicity StudiesBone health and osteoporosis researchHip disorders and treatments