Leukocyte adhesion to P-selectin and the inhibitory role of Crizanlizumab in sickle cell disease: A standardized microfluidic assessment
Yuncheng Man, Utku Goreke, Erdem Kucukal, Ailis Hill, Ran An, Shichen Liu, Allison Bode, Ambar Solis-Fuentes, Lalitha Nayak, Jane A. Little, Umut A. Gürkan
Topics & Concepts
AdhesionSelectinP-selectinCell adhesionImmunologyMedicineEndotheliumPlateletBiochipIn vitroE-selectinCell adhesion moleculePharmacologyChemistryPlatelet activationBiologyInternal medicineBioinformaticsBiochemistryOrganic chemistryHemoglobinopathies and Related DisordersBlood groups and transfusionErythrocyte Function and Pathophysiology