The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain
Tae‐Yang Jung, Baehyun Shin, Giorgio E. Tamò, Hyeongju Kim, Ravi Vijayvargia, Alexander Leitner, María J. Marcaida, Juan Astorga‐Wells, Roy Jung, Ruedi Aebersold, Matteo Dal Peraro, Hans Hebert, Ihn Sik Seong, Ji‐Joon Song
Topics & Concepts
HuntingtinPhosphorylationCell biologyChemistryHuntingtin ProteinFunction (biology)BiophysicsBiologyBiochemistryGeneMutantGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyFungal and yeast genetics research