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Preparation of mitochondria-targeted camptothecin derivatives for the imaging and antiproliferation of colorectal cancer

Chenmeng Xu, Rui Wang, Jia Li, Xiaomin Li, Jianjun Huang, Deshang Li, Qianqian Wang, Weijun Ma, Wim Dehaen, Hoa K. Chau, Yuyu Fang, Qiyong Huai

2025Bioorganic & Medicinal Chemistry5 citationsDOI

Topics & Concepts

CamptothecinChemistryRhodamine 123Colorectal cancerMitochondrionCancerPharmacologyCancer cellCytotoxicityFlow cytometryApoptosisRhodamineIn vitroCancer researchBiochemistryMolecular biologyInternal medicineFluorescenceBiologyMedicineMultiple drug resistanceAntibioticsPhysicsQuantum mechanicsCancer therapeutics and mechanismsATP Synthase and ATPases ResearchMitochondrial Function and Pathology
Preparation of mitochondria-targeted camptothecin derivatives for the imaging and antiproliferation of colorectal cancer | Litcius