Enhanced Ca2+-Driven Arrhythmogenic Events in Female Patients With Atrial Fibrillation
Xianwei Zhang, Yixuan Wu, Charlotte Smith, William E. Louch, Stefano Morotti, Dobromir Dobrev, Eleonora Grandi, Haibo Ni
Abstract
BACKGROUND: Substantial sex-based differences have been reported in atrial fibrillation (AF), but the underlying mechanisms are poorly understood. OBJECTIVES: -targeted interventions. METHODS: -targeted interventions were evaluated. RESULTS: -driven arrhythmogenic events in women, and revealed enhanced efficacy when applied in combination. CONCLUSIONS: -targeted interventions are promising therapeutic approaches in women.
Topics & Concepts
Atrial fibrillationCardiologyInternal medicineMedicineCardiac electrophysiology and arrhythmiasCardiovascular Effects of ExerciseAtrial Fibrillation Management and Outcomes