Litcius/Paper detail

Closing the gap: Systematic integration of multiplexed functional data resolves variants of uncertain significance in BRCA1, TP53, and PTEN

Shawn Fayer, Carolyn Horton, Jennifer N. Dines, Alan F. Rubin, Marcy E. Richardson, Kelly McGoldrick, Felicia Hernandez, Tina Pesaran, Rachid Karam, Brian H. Shirts, Douglas M. Fowler, Lea M. Starita

2021The American Journal of Human Genetics127 citationsDOIOpen Access PDF

Topics & Concepts

PTENComputational biologyClinical significanceBiologyPhenotypeGeneGeneticsBioinformaticsMedicinePI3K/AKT/mTOR pathwayPathologyApoptosisGenomics and Rare DiseasesCancer Genomics and DiagnosticsGene expression and cancer classification
Closing the gap: Systematic integration of multiplexed functional data resolves variants of uncertain significance in BRCA1, TP53, and PTEN | Litcius