Profiling of polar urine metabolite extracts from Chinese colorectal cancer patients to screen for potential diagnostic and adverse-effect biomarkers
Yi Deng, Houshan Yao, Wei Chen, Hua Wei, Xinxing Li, Feng Zhang, Shouhong Gao, Huan Man, Jing Chen, Tao Xia, Mingming Li, Wansheng Chen
Abstract
Background: Metabolomics has demonstrated its potential in the early diagnosis, drug safety evaluation and personalized toxicology research of various cancers.
Topics & Concepts
MedicineColorectal cancerMetabolomicsArea under the curveInternal medicineOncologyUrineMetaboliteAdverse effectReceiver operating characteristicLogistic regressionPharmacologyBioinformaticsCancerBiologyMetabolomics and Mass Spectrometry StudiesPARP inhibition in cancer therapyHematological disorders and diagnostics