A photoresponsive antibody–siRNA conjugate for activatable immunogene therapy of cancer
Xingxing Wang, Xiao Xiao, Yi Feng, Jinbo Li, Yan Zhang
Abstract
. This study thus provides a useful conditional delivery platform for siRNAs and a novel means for activatable cancer immunogene therapy.
Topics & Concepts
Small interfering RNAIn vivoLinkerIntracellularCancer researchChemistryCancer cellCancerEndocytosisCell biologyCancer immunotherapyTransfectionMolecular biologyBiophysicsImmunotherapyBiologyCellBiochemistryGeneComputer scienceBiotechnologyGeneticsOperating systemRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesImmunotherapy and Immune Responses