An Insight on the Prospect of Quinazoline and Quinazolinone Derivativesas Anti-tubercular Agents
Namrata Kushwaha, Adarsh Sahu, Jyotika Mishra, Ankit Soni, Dhawal Dorwal
Abstract
Multiple potential drugs have been developed based on the heterocyclic molecules for the treatment of different symptoms. Among the existing heterocyclic molecules, quinazoline and quinazolinone derivatives have been found to exhibit extensive pharmacological and biological characteristics. One significant property of these molecules is their potency as anti-tubercular agents. Thus, both quinazoline and quinazolinone derivatives are modified using different functional groups as substituents for investigating their anti-tubercular activities. We present a summary of the reported anti-tubercular drugs, designed using quinazoline and quinazolinone derivatives, in this review.