Glucosylation mechanism of resveratrol through the mutant Q345F sucrose phosphorylase from the organism <i>Bifidobacterium adolescentis</i>: a computational study
Camilo Febres-Molina, Leslie Sánchez, Xavier Prat‐Resina, Gonzalo A. Jaña
Abstract
) together with two water molecules at the active site strongly contribute to the stabilization of the transition state. The understanding of this glucosylation mechanism of the polyphenol resveratrol carried out by the mutant sucrose phosphorylase enzyme presented in this work could serve as the basis for subsequent studies on related carbohydrate-active enzymes.
Topics & Concepts
ChemistryResveratrolEnzymeBiochemistryPolyphenolMutantStereochemistryBiophysicsAntioxidantBiologyGeneEnzyme Structure and FunctionBiochemical and Molecular ResearchEnzyme Production and Characterization