Design, synthesis, and molecular modeling studies of novel 2-quinolone-1,2,3-triazole-α-aminophosphonates hybrids as dual antiviral and antibacterial agents
Khadija El Gadali, Meriem Rafya, Az‐eddine El Mansouri, Mohamed Maatallah, Arie Van-Der-Lee, Ahmad Mehdi, Johan Neyts, Dirk Jochmans, Steven De Jonghe, Fatiha Benkhalti, Yogesh S. Sanghvi, Moha Taourirte, Hassan B. Lazrek
Topics & Concepts
ChemistryStereochemistryADMEQuinoloneAntibacterial activityDocking (animal)PharmacophoreBacteriaBiochemistryAntibioticsIn vitroBiologyMedicineGeneticsNursingHIV/AIDS drug development and treatmentPneumocystis jirovecii pneumonia detection and treatmentBiochemical and Molecular Research