Design, synthesis of novel triptolide-glucose conjugates targeting glucose Transporter-1 and their selective antitumor effect
Yan Liu, Jiaqing Huang, Min Wu, Liu Bi, Qiaofa Lin, Jingjing Wu, Yuhua Ouyang, Xin Guo, Ruyi Huang, Yongmin Zhang, Jianhua Xu
Topics & Concepts
TriptolideCytotoxicityChemistryProdrugIn vivoApoptosisPharmacologyGlucose transporterIn vitroConjugateBiochemistryCancer researchBiologyEndocrinologyMathematicsBiotechnologyInsulinMathematical analysisNatural Compounds in Disease TreatmentHistone Deacetylase Inhibitors ResearchCancer therapeutics and mechanisms