1-Deazaguanosine-Modified RNA: The Missing Piece for Functional RNA Atomic Mutagenesis
Raphael Bereiter, Eva Renard, Kathrin Breuker, Christoph Kreutz, Eric Ennifar, Ronald Micura
Abstract
G-modified RNA and demonstrates the power of the completed deazanucleoside toolbox for RNA atomic mutagenesis needed to achieve in-depth understanding of RNA recognition and catalysis.
Topics & Concepts
ChemistryRNAMutagenesisRna processingComputational biologyBiochemistryMutationGeneBiologyRNA and protein synthesis mechanismsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniques