Preparation of a disposable electrochemiluminescence sensor chip based on an MXene-loaded ruthenium luminescent agent and its application in the detection of carcinoembryonic antigens
Weiwei Luo, Zhuoxin Ye, Pinyi Ma, Qiong Wu, Daqian Song
Abstract
. The chip was used to determine CEA in the serum of healthy humans and cancer patients, and the results were consistent with those obtained using ELISA. The disposable ECL sensor chip has many advantages including convenience, rapid detection, low cost and easy mass production; thus it has great application potential in clinical cancer diagnosis.
Topics & Concepts
ElectrochemiluminescenceCarcinoembryonic antigenDetection limitRutheniumElectrodeImmunoassayChipMaterials scienceChemistryNanotechnologyCombinatorial chemistryChromatographyComputer scienceCancerCatalysisMedicineAntibodyBiochemistryTelecommunicationsInternal medicinePhysical chemistryImmunologyAdvanced biosensing and bioanalysis techniquesMXene and MAX Phase MaterialsNanopore and Nanochannel Transport Studies